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Title: The definition of specific antiparkinsonian effects of Rapitalam
Authors: Avdeeva, N. V.
Pokrovskiy, M. V.
Zhernakova, N. I.
Artyushkova, E. B.
Keywords: medical
Parkinson's disease
metabotropic glutamate receptor
Issue Date: 2018
Citation: The definition of specific antiparkinsonian effects of Rapitalam / N. V. Avdeeva, M. V. Pokrovskiy, N. I. Zhernakova [et al.] // Journal of International Pharmaceutical Research. - 2018. - Vol.45.- P. 430-434.
Abstract: Previously, we identified a metabotropic glutamate receptor 4 (mGluR4) as a potential target for drugs and predicted that activation of mGluR4 could provide a palliative advantage in the treatment of Parkinson's disease. Determine the mechanism of action of Rapitalam in vitro on a cell culture with mGluR4 over expression. The HEK293T cell line expressing human mGluR4 was used in the work
Appears in Collections:Статьи из периодических изданий и сборников (на иностранных языках) = Articles from periodicals and collections (in foreign languages)

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