http://dspace.bsu.edu.ru/handle/123456789/54601| Title: | The impact of genetic polymorphisms in glutamate-cysteine ligase, a key enzyme of glutathione biosynthesis, on Ischemic stroke risk and brain infarct size |
| Authors: | Polonikov, A. Bocharova, I. Azarova, I. Klyosova, E. Churnosov, M. |
| Keywords: | medicine medical genetics genes GCLC GCLM single nucleotide polymorphism gene-gene interactions gene-environment interactions ischemic stroke brain infarction oxidative stress glutathione |
| Issue Date: | 2022 |
| Citation: | The impact of genetic polymorphisms in glutamate-cysteine ligase, a key enzyme of glutathione biosynthesis, on Ischemic stroke risk and brain infarct size / A. Polonikov [et al.] // Life. - 2022. - Vol.12, №4.-Art. 602. - Doi: 10.3390/ life12040602. - URL: https://www.mdpi.com/2075-1729/12/4/602. |
| Abstract: | The purpose of this pilot study was to explore whether polymorphisms in genes encoding the catalytic (GCLC) and modifier (GCLM) subunits of glutamate-cysteine ligase, a rate-limiting enzyme in glutathione synthesis, play a role in the development of ischemic stroke (IS) and the extent of brain damage |
| URI: | http://dspace.bsu.edu.ru/handle/123456789/54601 |
| Appears in Collections: | Статьи из периодических изданий и сборников (на иностранных языках) = Articles from periodicals and collections (in foreign languages) |
| File | Description | Size | Format | |
|---|---|---|---|---|
| Polonikov_Impact_22.pdf | 2.17 MB | Adobe PDF | View/Open |
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