http://dspace.bsu.edu.ru/handle/123456789/41271| Title: | Сandidate genes for age at menarche are associated with uterine leiomyoma |
| Authors: | Ponomarenko, I. Reshetnikov, E. Polonikov, A. Verzilina, I. Churnosov, M. |
| Keywords: | medicine medical genetics age at menarche association gene-environment interactions gene-gene interaction single nucleotide polymorphism uterine leiomyoma |
| Issue Date: | 2021 |
| Citation: | Сandidate genes for age at menarche are associated with uterine leiomyoma / I. Ponomarenko [et al.] // Frontiers in Genetics. - 2021. - Vol.11.-Art. 512940. - Doi: 10.3389/fgene.2020.512940. - URL: https://www.frontiersin.org/articles/10.3389/fgene.2020.512940/full |
| Abstract: | Age at menarche (AAM) is an important marker of the pubertal development and function of the hypothalamic-pituitary-ovarian system. It was reported as a possible factor for a risk of uterine leiomyoma (UL). However, while more than 350 loci for AAM have been determined by genome-wide association studies (GWASs) to date, no studies of these loci for their association with UL have been conducted so far. In this study, we analyzed 52 candidate loci for AAM for possible association with UL in a sample of 569 patients and 981 controls |
| URI: | http://dspace.bsu.edu.ru/handle/123456789/41271 |
| Appears in Collections: | Статьи из периодических изданий и сборников (на иностранных языках) = Articles from periodicals and collections (in foreign languages) |
| File | Description | Size | Format | |
|---|---|---|---|---|
| Ponomarenko_Сandidate.pdf | 2.67 MB | Adobe PDF | View/Open |
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