http://dspace.bsu.edu.ru/handle/123456789/34316| Title: | The study of the associations of polymorphism of matrix metalloproteinases with multifactorial human diseases and in silico assessment of their functional effects |
| Authors: | Minyaylo, O. I. Starikova, D. I. Orlova, V. S. Batlutskaya, I. V. Efremova, O. A. Kulikovsky, V. F. |
| Keywords: | medicine medical genetics gene polymorphism matrix metalloproteinases genomic DNA multifactorial pathology arterial hypertension primary open-angle glaucoma peptic ulcer |
| Issue Date: | 2020 |
| Citation: | The study of the associations of polymorphism of matrix metalloproteinases with multifactorial human diseases and in silico assessment of their functional effects / O.I. Minyaylo, D.I. Starikova, V.S. Orlova [et al.] // EurAsian Journal of BioSciences. - 2020. - Vol. 14. - P. 1995-1998. - Refer.: p. 1997-1998. |
| Abstract: | The objective of this study is to identify the associations of polymorphism of matrix metalloproteinase genes with multifactorial diseases and evaluate in silico their functional effects. The material for the study was genomic DNA isolated from venous blood samples by the standard phenol-chloroform extraction method. The rs2250889 MMP9, rs11568818 MMP7 and rs17576 MMP9 polymorphic loci were studied using the polymerase chain reaction on a CFX-96 Real-Time System thermal cycler (Bio-Rad Laboratories, Inc., US) using oligonucleotide primers and probes synthesized by Syntol LLC, Russia) |
| URI: | http://dspace.bsu.edu.ru/handle/123456789/34316 |
| Appears in Collections: | Статьи из периодических изданий и сборников (на иностранных языках) = Articles from periodicals and collections (in foreign languages) |
| File | Description | Size | Format | |
|---|---|---|---|---|
| Minyaylo_Study.pdf | 314.7 kB | Adobe PDF | View/Open |
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