http://dspace.bsu.edu.ru/handle/123456789/63422| Title: | Identification and synthesis of metabolites of the new 4.5-dihydroisoxazol-5-carboxamide derivate |
| Authors: | Khokhlov, A. L. Yaichkov, I. I. Alexeev, M. A. Korsakov, M. K. Shetnev, A. A. |
| Keywords: | medicine pharmacology 4.5-dihydroisoxazol-5-carboxamide derivative biotransformation PAR-2 inhibitor hydrolysis |
| Issue Date: | 2024 |
| Citation: | Identification and synthesis of metabolites of the new 4.5-dihydroisoxazol-5-carboxamide derivate / A.L. Khokhlov, I.I. Yaichkov, M.A. Alexeev [et al.] // Research Results in Pharmacology. - 2024. - Vol.10, №2.-P. 83-95. - Doi: 10.18413/rrpharmacology.10.482. - Refer.: p. 94. |
| Abstract: | 3-(2-butyl-5-chloro-1H-imidazole-4-yl)-N-[4-methoxy-3-(trifluoromethyl)phenyl]-4,5- dihydro-1,2-oxazole-5-carboxamide is new antirheumatic drug. It is necessary to identify and synthesize the biotransformation products for its complete pharmacokinetic study |
| URI: | http://dspace.bsu.edu.ru/handle/123456789/63422 |
| Appears in Collections: | Vol. 10, № 2 |
| File | Description | Size | Format | |
|---|---|---|---|---|
| Yaichkov_Identification_24.pdf | 790.93 kB | Adobe PDF | View/Open |
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