| DC Field | Value | Language |
|---|
| dc.contributor.author | Bykanova, M. A. | - |
| dc.contributor.author | Solodilova, M. A. | - |
| dc.contributor.author | Azarova, I. E. | - |
| dc.contributor.author | Klyosova, E. Y. | - |
| dc.contributor.author | Churnosov, M. | - |
| dc.date.accessioned | 2023-03-21T13:15:37Z | - |
| dc.date.available | 2023-03-21T13:15:37Z | - |
| dc.date.issued | 2022 | - |
| dc.identifier.citation | Genetic variation at the catalytic subunit of glutamate cysteine ligase contributes to the susceptibility to sporadic colorectal cancer: a pilot study / M.A. Bykanova [et al.] // Molecular Biology Reports. - 2022. - Vol.49.-P. 6145-6154. - Doi: 10.1007/s11033-022-07406-0. - Refer.: p. 6152-6154. | ru |
| dc.identifier.uri | http://dspace.bsu.edu.ru/handle/123456789/52322 | - |
| dc.description.abstract | Glutathione is a tripeptide detoxifying a variety of exogenous and endogenous free radicals and carcinogens, and a deficiency of glutathione is associated with an increased host susceptibility to oxidative stress, a pathological condition implicated in the development and progression of cancer. The catalytic subunit of glutamate-cysteine ligase (GCLC) is an enzyme responsible for the initial and rate-limiting step of glutathione biosynthesis | ru |
| dc.language.iso | en | ru |
| dc.subject | medicine | ru |
| dc.subject | medical genetics | ru |
| dc.subject | colorectal cancer | ru |
| dc.subject | carcinogenesis | ru |
| dc.subject | genetic predisposition | ru |
| dc.subject | single nucleotide polymorphism | ru |
| dc.subject | glutamate cysteine ligase | ru |
| dc.subject | glutathione | ru |
| dc.title | Genetic variation at the catalytic subunit of glutamate cysteine ligase contributes to the susceptibility to sporadic colorectal cancer: a pilot study | ru |
| dc.type | Article | ru |
| Appears in Collections: | Статьи из периодических изданий и сборников (на иностранных языках) = Articles from periodicals and collections (in foreign languages)
|
