| DC Field | Value | Language |
|---|
| dc.contributor.author | Potapov, A. Yu. | - |
| dc.contributor.author | Paponov, B. V. | - |
| dc.contributor.author | Podoplelova, N. A. | - |
| dc.contributor.author | Panteleev, M. A. | - |
| dc.contributor.author | Potapov, M. A. | - |
| dc.date.accessioned | 2023-03-14T09:07:27Z | - |
| dc.date.available | 2023-03-14T09:07:27Z | - |
| dc.date.issued | 2021 | - |
| dc.identifier.citation | Synthesis of 2H-pyrano[3,2-g]quinolin-2-ones containing a pyrimidinone moiety and characterization of their anticoagulant activity via inhibition of blood coagulation factors Xa and XIa / Potapov A.Yu. [et al.] // Chemistry of Heterocyclic Compounds. - 2021. - Vol.57, №5.-P. 574-580. | ru |
| dc.identifier.uri | http://dspace.bsu.edu.ru/handle/123456789/52115 | - |
| dc.description.abstract | The reactions of 7-hydroxy-1,2,2,4-tetramethylhydroquinoline-6-carbaldehydes with methyl 3-oxopentanedioate were used to synthesize 3-oxo-3-(6,8,8,9-tetramethyl-2-oxo-2H-pyrano[3,2-g]quinolin-3-yl)propanoates with various degrees of hydrogenation in the pyridine ring, the condensation of which with carboximidamides provided a series of new 6,8,8,9-tetramethyl-3-(6-oxo-1,6-dihydropyrimidin- 4-yl)-2H-pyrano[3,2-g]quinolin-2-ones. It was found that some compounds of this class exhibited relatively high inhibitory activity against the blood coagulation factors Xа and XIa | ru |
| dc.language.iso | en | ru |
| dc.subject | chemistry | ru |
| dc.subject | organic chemistry | ru |
| dc.subject | carboximidamide | ru |
| dc.subject | methyl 2-oxo-(2H-pyrano[3,2-g]quinolin-3-yl)propanoate | ru |
| dc.subject | pyrano[3,2-g]quinoline | ru |
| dc.subject | pyrimidine | ru |
| dc.subject | factor Xa | ru |
| dc.subject | factor XIa | ru |
| dc.subject | molecular hybridization | ru |
| dc.title | Synthesis of 2H-pyrano[3,2-g]quinolin-2-ones containing a pyrimidinone moiety and characterization of their anticoagulant activity via inhibition of blood coagulation factors Xa and XIa | ru |
| dc.type | Article | ru |
| Appears in Collections: | Статьи из периодических изданий и сборников (на иностранных языках) = Articles from periodicals and collections (in foreign languages)
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