|Title:||Evaluation of the pharmacological activity of hybrid organotin compounds in a B16 melanoma model in the classical and metronomic administration modes|
|Authors:||Dodokhova, M. A.|
Safronenko, A. V.
Kotieva, I. M.
Alkhuseyn-Kulyaginova, M. S.
Shpakovsky, D. B.
metronomic drug administration
|Citation:||Evaluation of the pharmacological activity of hybrid organotin compounds in a B16 melanoma model in the classical and metronomic administration modes / M.A. Dodokhova [et al.] // Research Results in Pharmacology. - 2022. - Vol.8, №1.-P. 85-93. - Doi: 10.3897/rrpharmacology.8.76363.|
|Abstract:||In modern medical chemistry, much attention is paid to the search for new antimetastatic agents based on metal compounds. Organotin compounds promise to be good candidates as the treatment of malignant neoplasms. In order to reduce a possible nonspecific toxic effect of tin compounds and to expand the intended therapeutic use, the paper presents hybrid tin (IV) complexes with Sn-S bond containing a fragment of 2,6-di-tert-butylphenol|
|Appears in Collections:||Vol. 8, № 1|
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