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dc.contributor.authorBuchelnikov, A. S.-
dc.contributor.authorEvstigneev, M. P.-
dc.date.accessioned2017-10-12T12:09:58Z-
dc.date.available2017-10-12T12:09:58Z-
dc.date.issued2014-
dc.identifier.citationBuchelnikov, A.S. Quantitative correlation of the in vitro biological effect with parameters of molecular complexation in mutagen-interceptor systems / A. S. Buchelnikov, M. P. Evstigneev // Journal of Theoretical Biology. - 2014. - Vol.357.-P. 268-271.ru
dc.identifier.urihttp://dspace.bsu.edu.ru/handle/123456789/20215-
dc.description.abstractAccording to the theory of interceptor-protector action a quantitative link between the physico-chemical parameters of molecular complexation and in vitro biological effect in aromatic drug-interceptor systems must exist. In the present communication such link between relative change in mutagenicity of IQ-type aromatic mutagens on addition of aromatic interceptor molecules with equilibrium hetero-association constants of mutagen-interceptor complexation has been found using the published in vitro data in bacteria cell systemsru
dc.language.isoenru
dc.subjectbiologyru
dc.subjectmolecular biologyru
dc.subjectmolecular biochemistryru
dc.subjectaromatic biologically active compoundsru
dc.subjectIQ-type mutagensru
dc.subjectmutagenic testru
dc.subjectinterceptor mechanismru
dc.subjecthetero-associationru
dc.titleQuantitative correlation of the in vitro biological effect with parameters of molecular complexation in mutagen-interceptor systemsru
dc.typeArticleru
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