Skip navigation
BelSU DSpace logo

Please use this identifier to cite or link to this item: http://dspace.bsu.edu.ru/handle/123456789/29269
Title: Endothelioprotective property of the combination of the thioctic acid and rosuvastatin shown in the endothelial dysfunction models
Authors: Molchanova, O. V.
Pokrovskaya, T. G.
Povetkin, S. V.
Reznikov, K. M.
Keywords: medicine
pharmacology
endothelial dysfunction
L-NAME
thioctic acid
rosuvastatin
nitric oxide
oxidative stress
ovarioectomy
Issue Date: 2016
Citation: Endothelioprotective property of the combination of the thioctic acid and rosuvastatin shown in the endothelial dysfunction models / O.V. Molchanova [et al.] // Research Result: Pharmacology and Clinical Pharmacology. - 2016. - Vol.2, №1(2).-P. 9-15. - Doi: 10.18413/2313-8971-2016-2-1-9-15. - Refer.: p. 14-15.
Abstract: During the experiment, the modeling of endothelial dysfunction of male rats was performed by intraperitoneal administration of L-NAME at a dose of 25 mg/kg for 7 days, and the same of female rats was performed by bilateral ovarioectomy and further intraperitoneal administration of L-NAME at a dose of 25 mg/kg for 7. The deficiency of nitric oxide as a result of the NO-synthase blockade was accompanied by the impairment of the endotheliumdependent and independent vasodilatation estimated in the pharmacological tests, which was expressed in the increasing coefficient of endothelial dysfunction
URI: http://dspace.bsu.edu.ru/handle/123456789/29269
Appears in Collections:Research Result. Pharmacology and Clinical Pharmacology

Files in This Item:
File Description SizeFormat 
Pokrovskaya_Endothelioprotective.pdf1.09 MBAdobe PDFView/Open
Show full item record


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.