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Title: Interaction between some antibiotics and antioxidants
Authors: Miroshnichenko, A. G.
Perfilyev, V. Yu.
Lysenko, I. V.
Zhernakova, N. I.
Keywords: medicine
physiology of animals
antibacterial agents
Klebsiella pneumoniae
Escherichia coli
drug interactions
Issue Date: 2017
Citation: Interaction between some antibiotics and antioxidants» / A.G. Miroshnichenko [et al.] // Research result. Pharmacology and clinical pharmacology. - 2017. - Vol.3, №4.-P. 100-112. - DOI: 10.18413/2313-8971-2017-3-4-100-112. - Refer.: p. 111-112.
Series/Report no.: Pharmacology and clinical pharmacology;
Abstract: The study examined the interaction of antibiotics (gentamicin, ciprofloxacin, ceftazidime) and antioxidants (ascorbic acid, N-acetylcysteine, methylethylpyridinol) in vitro and in vivo. We conducted a dynamic study of the effect of antioxidants at concentrations of 0.5, 1, 2 and 4 mM on the activity of antibacterial agents in vitro for three strains of Klebsiella pneumoniae and three strains of Escherichia coli. The effect of antioxidants on the effectiveness of antibacterial therapy was studied in Wistar rats with experimental bacterial peritonitis
Appears in Collections:Research Result. Pharmacology and Clinical Pharmacology

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