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Title: Study of analeptic activity of tetrahydropyrido [2,1-b] [1,3,5] tiadiazine derivatives
Authors: Bibik, E. Yu.
Saphonova, A. A.
Yeryomin, A. V.
Frolov, K. A.
Dotsenko, V. V.
Keywords: medicine
physiology of animals
analeptic activity
derivatives of tetrahydropyrido thiadiazine
thiopental sodium
caffein-sodium benzoate
Issue Date: 2017
Citation: Study of analeptic activity of tetrahydropyrido [2,1-b] [1,3,5] tiadiazine derivatives / Bibik E.Yu. [et al.] // Research result. Pharmacology and clinical pharmacology. - 2017. - Vol.3, №4.- P. 20-25. - DOI: 10.18413/2313-8971-2017-3-4-20-25. - Refer.: p. 25.
Series/Report no.: Pharmacology and clinical pharmacology;
Abstract: Our goal is to conduct an investigation of the analeptic activity of the tetrahydropyrido [2,1-b] [1, 3, 5] thiadiazine derivative group. Biological studies were carried out on 78 white pedigreed mature sexually transmitted rats of both sexes weighing 230-270 g in the autumn-winter period. The test substances were administered intragastrically at a dose of 5 mg/kg 1 hour prior to the induction of anesthesia. Animals of the control group received thiopental sodium at a dose of 70 mg/kg. As the reference preparation, sodium caffeinebenzoate was used intraperitoneally at a dose of 10 mg/kg
Appears in Collections:Research Result. Pharmacology and Clinical Pharmacology

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