Skip navigation
BelSU DSpace logo

Please use this identifier to cite or link to this item: http://dspace.bsu.edu.ru/handle/123456789/21467
Title: Interleukin-6 is a potential target for a correction of endothelial dysfunction associated with low-grade systemic inflammation
Authors: Kostina, D. A.
Pokrovskaya, T. G.
Beskhmelnitsyna, E. A.
Keywords: medicine
internal illnesses
endothelial dysfunction
low-grade systemic inflammation
interleukin-6
tocilizumab
Issue Date: 2017
Citation: Kostina, D.A. Interleukin-6 is a potential target for a correction of endothelial dysfunction associated with low-grade systemic inflammation / D.A. Kostina, T.G. Pokrovskaya, E.A. Beskhmelnitsyna // Research result. Pharmacology and clinical pharmacology. - 2017. - Vol.3, №3.-P. 89-96. - DOI: 10.18413/2313-8971-2017-3-3-89-96.
Abstract: One of pathogenetic links of development of endothelial dysfunction, as an early marker of cardiovascular disease and comorbidity, is a low-grade systemic inflammation. In this regard, correction of cytokines imbalance is one of the possible ways of prevention and treatment of major chronic noninfectious diseases. To study the endothelium protective effects of anti-IL-6 receptor monoclonal antibodies tocilizumab in experimental preclinical studies in a model of endothelial dysfunction associated with the low-grade systemic inflammation
URI: http://dspace.bsu.edu.ru/handle/123456789/21467
Appears in Collections:Research Result. Pharmacology and Clinical Pharmacology

Files in This Item:
File Description SizeFormat 
Kostina_Interleukin_17.pdf1.27 MBAdobe PDFView/Open
Show full item record


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.