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Please use this identifier to cite or link to this item: http://dspace.bsu.edu.ru/handle/123456789/19839
Title: Dermatoprotective activity of a combination of enoxifol with rexod in a reduced form the blood circulation in the skin in diabetes mellitus and hypercholesterinemia
Authors: Seletskaya, V. V.
Galenko-Yaroshevskii, P. A.
Keywords: medicine
pharmacology
enoxifol
rexod
the combination of enoxifol with rexod
alloxanic diabetes mellitus
exogenous hypercholesterinemia
experiments
Issue Date: 2017
Citation: Seletskaya, V.V. Dermatoprotective activity of a combination of enoxifol with rexod in a reduced form the blood circulation in the skin in diabetes mellitus and hypercholesterinemia / V. V. Seletskaya, P. A. Galenko-Yaroshevskii // Research result. Pharmacology and clinical pharmacology. - 2017. - Vol.3, №1.-P. 32-48. - DOI : 10.18413/2500-235X-2017-3-1-32-48. - Refer.: p. 47-48.
Abstract: Experiments in rats showed that the 9-diethylaminoethyl-2-(3,4-dioxyphenyl)-imidazo- [1,2-a]-benzimidazole dihydrobromide with the provisional name of enoxifol (0.94 - 15 mg/kg), rexod (recombinant human superoxide dismutase; 0.002 mg/kg) and especially their combination in intravenous administration in a reduced blood circulation in the skin against the background of the normoglycemia and hyperglycemia induced by experimental (alloxanic) diabetes mellitus complicated by exogenous hypercholesterinemia have a pronounced dose-dependent dermatoprotective effect, which may be due to the activation of energy processes and increase the reserve capacity of the antioxidant support network and normalization of carbohydrate and lipid metabolism
URI: http://dspace.bsu.edu.ru/handle/123456789/19839
Appears in Collections:Research Result. Pharmacology and Clinical Pharmacology

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