|Title:||Dermatoprotective activity of a combination of enoxifol with rexod in a reduced form the blood circulation in the skin in diabetes mellitus and hypercholesterinemia|
|Authors:||Seletskaya, V. V.|
Galenko-Yaroshevskii, P. A.
the combination of enoxifol with rexod
alloxanic diabetes mellitus
|Citation:||Seletskaya, V.V. Dermatoprotective activity of a combination of enoxifol with rexod in a reduced form the blood circulation in the skin in diabetes mellitus and hypercholesterinemia / V. V. Seletskaya, P. A. Galenko-Yaroshevskii // Research result. Pharmacology and clinical pharmacology. - 2017. - Vol.3, №1.-P. 32-48. - DOI : 10.18413/2500-235X-2017-3-1-32-48. - Refer.: p. 47-48.|
|Abstract:||Experiments in rats showed that the 9-diethylaminoethyl-2-(3,4-dioxyphenyl)-imidazo- [1,2-a]-benzimidazole dihydrobromide with the provisional name of enoxifol (0.94 - 15 mg/kg), rexod (recombinant human superoxide dismutase; 0.002 mg/kg) and especially their combination in intravenous administration in a reduced blood circulation in the skin against the background of the normoglycemia and hyperglycemia induced by experimental (alloxanic) diabetes mellitus complicated by exogenous hypercholesterinemia have a pronounced dose-dependent dermatoprotective effect, which may be due to the activation of energy processes and increase the reserve capacity of the antioxidant support network and normalization of carbohydrate and lipid metabolism|
|Appears in Collections:||Research Result. Pharmacology and Clinical Pharmacology|
|Seletskaya_Dermatoprotective_17.pdf||1.29 MB||Adobe PDF||View/Open|
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