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Please use this identifier to cite or link to this item: http://dspace.bsu.edu.ru/handle/123456789/19832
Title: Pharmacological efficacy of an inhibitor of arginase-2 KUD975 with L-NAME-induced endothelial dysfunction
Authors: Kudryavtsev, K. V.
Korokin, M. V.
Gudyrev, O. S.
Keywords: medicine
pharmacology
endothelial dysfunction
arginase inhibitors
compounds of phenolic nature
Issue Date: 2017
Citation: Kudryavtsev, K.V. Pharmacological efficacy of an inhibitor of arginase-2 KUD975 with L-NAME-induced endothelial dysfunction / K. V. Kudryavtsev, M. V. Korokin, O. S. Gudyrev // Research result. Pharmacology and clinical pharmacology. - 2017. - Vol.3, №1.-P. 10-17. - DOI : 10.18413/2500-235X-2017-3-1-10-17. - Refer.: p. 17.
Abstract: The study of endotelio- and cardioprotective activity of finished dosage forms - tablets, film-coated, containing 10 mg of phenolic nature KUD-975, was shown a statistically significant decrease in blood pressure and the coefficient of endothelial dysfunction on the background of simulation L-NAME-induced pathology. In the group of animals treated with KUD975 found a statistically significant increase in the concentrations of stable metabolites of nitric oxide, which in addition to the normalization of vasodilation says about endothelioprotektive action of the compounds studied
URI: http://dspace.bsu.edu.ru/handle/123456789/19832
Appears in Collections:Research Result. Pharmacology and Clinical Pharmacology

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