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Title: Pharmacological evaluation polysaccharide complex flowers tansy
Authors: Yakusheva, E. N.
Engalycheva, E. E.
Sychev, I. A.
Shculkin, A. V.
Keywords: medicine
flowers of Tansy
anti-inflammatory activity
antioxidant effect
gastroprotective activity
gepatoprotective activity
Issue Date: 2016
Citation: Pharmacological evaluation polysaccharide complex flowers tansy / E. N. Yakusheva [et al.] // Research result: pharmacology and clinical pharmacology. - 2016. - Vol.2, №4.- P. 45-54. - DOI: 10.18413/250 0-235X-2016-2-4-45-54. - Refer.: p. 53-54.
Abstract: From flowers tansy extracted polysaccharide complex. Installed its qualitative and quantitative composition, have developed a technique standardizing the content of reducing sugars. By thin layer chromatography and high pressure liquid chromatography after acid hydrolysis installed monosaccharide composition: glucose, xylose, arabinose, galactose and mannose. It is proved that the polysaccharide has a high content of uronic acid, which allows it to include the class of pectin. The investigation of gastroprotective activity of polysaccharide in the prophylactic administration at model destruction of the gastric mucosa to indomethacin. Introduction polysaccharide prevents various types of erosive and ulcerative destruction. According to anti-ulcer activity of the drug is superior to ranitidine and comparable to omeprazole
Appears in Collections:Research Result. Pharmacology and Clinical Pharmacology

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