|Title:||Experimental investigation of pharmacokinetic properties and the accumulation of zinc when administrated nanoform of zinc hydroxide in a comparative aspect with zinc sulfate|
|Authors:||Larin, S. L.|
Zvyagintseva, A. R.
Habarov, A. A.
Budko, E. V.
physiology of animals
|Citation:||Experimental investigation of pharmacokinetic properties and the accumulation of zinc when administrated nanoform of zinc hydroxide in a comparative aspect with zinc sulfate / S. L. Larin [et al.] // Research result: pharmacology and clinical pharmacology. - 2016. - Vol.2, №4.- P. 21-33. - DOI: 10.18413/2500-235X -2016-2-4-21-33. - Refer.: p. 33.|
|Abstract:||The purpose of a preliminary assessment of the biological effect, a comparative study of nanoparticles using test cultures of bakery yeast, the results of which determined the level of inhibition, which was higher than 90%, compared with the figure for the zinc sulfate and the above 145% more compared to the zinc oxide. Investigation was performed on the pharmacokinetic characteristics of the 40 rabbits-males in comparison with that using zinc sulfate, in an enteral or intravenous administration at three dose levels: 10, 50 and 100 mg/kg|
|Appears in Collections:||Research Result. Pharmacology and Clinical Pharmacology|
|Larin_Experimental_16.pdf||921.52 kB||Adobe PDF||View/Open|
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