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Please use this identifier to cite or link to this item: http://dspace.bsu.edu.ru/handle/123456789/17480
Title: Correction of ischemic damage to the retina on application of pharmacological preconditioning of recombinant erythropoietin
Authors: Shabelnikova, A. S.
Keywords: medicine
pharmacology
ischemia-reperfusion of the retina
pharmacological preconditioning
erythropoietin
emoxipine
ATP-dependent potassium channels
Issue Date: 2016
Citation: Shabelnikova, A.S. Correction of ischemic damage to the retina on application of pharmacological preconditioning of recombinant erythropoietin / A. S. Shabelnikova // Research Result: Pharmacology and Clinical Pharmacology. - 2016. - Vol.2, №2(3).-P. 67-90. - DOI : 10.18413/2313-8971-2016-2-2-67-90. - Refer.: p. 88-90.
Abstract: To study the protective properties of pharmacological preconditioning with recombinant erythropoietin suberitro stimulating dose of 50 IU / kg in the retina of the eye, was the model of retinal ischemia, ischemia with the assessment of the temporary simulation mode of the retina of rats with the instrumental methods of analysis and morphometric studies. The most suitable model was a model 30 minute ischemia with subsequent reperfusion periods of 1 hour to 72 hours. We studied the protective effect preconditioning suberitro stimulating recombinant erythropoietin in a dose of 50 IU/kg, preconditioning distant ischemic and emoxipine 2 mg/kg per rat model of retinal ischemia
URI: http://dspace.bsu.edu.ru/handle/123456789/17480
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