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Please use this identifier to cite or link to this item: http://dspace.bsu.edu.ru/handle/123456789/16313
Title: Correction of adma-induced preeclampsia with the use of phosphodiesterase 5 and selective inhibitor of arginase II ZB49-0010
Authors: Gureev, V. V.
Martynova, O. V.
Anciferova, O. E.
Martynov, M. A.
Pokrovskaia, T. G.
Keywords: medicine
obstetrics
pathological obstetrics
pathology of pregnancy
pharmacology
N-nitro-L-arginine methyl ester
endothelial dysfunction
preeclampsia
phosphodiesterase 5
selective inhibitor of arginase II
rats
Issue Date: 2015
Citation: Correction of adma-induced preeclampsia with the use of phosphodiesterase 5 and selective inhibitor of arginase II ZB49-0010 / V. V. Gureev [и др.] // Научный результат. Сер. Медицина и фармация. - 2015. - Т.1, №4(6).-С. 66-68. - doi: 10.18413/2313-8955-2015-1-4-66-68.
Abstract: Simulation experimental ADMA-like preeclampsia was carried out by administering the rats with L-NAME during 14-20 days of pregnancy. In animals, there was an increase in blood pressure, proteinuria, impaired microcirculation in the placenta, the violation of the regulation of vascular tone and destructive changes in the ischemic placenta. The use of phosphodiesterase 5 and selective inhibitor of arginase II ZB49-0010 leads to the expression of morphological and functional correction of violations occurring in modeling of experimental preeclampsia
URI: http://dspace.bsu.edu.ru/handle/123456789/16313
Appears in Collections:Научный результат. Сер. Медицина и фармация

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